Contents

1. Introduction to Genetics

1.1 Introduction

1.2 Recapitulation of mendelian genetics and its practical applications

1.3 Practical applications of genetics

1.4 Mendelian laws

2. Multiple Alleles

2.1 Concept of multiple alleles

2.2 Coat color in mus musculus

2.3 ABO blood group system

2.4 Concept of multiple gene (Polygenic Inheritance) with reference to skin colour in man.

2.5 Concept of pleiotropy

3. Gene Interaction

3.1 Concept of gene interaction

3.2 Complementary factors (9:7)

3.3 Supplementary factors (9:3:4)

3.4 Inhibitory factors (13:3)

3.5 Duplicate factors (15:1)

3.6 Lethal genes (Dominant and Recessive)

4. Chromosomes

4.1 Introduction

4.2 Morphology of the chromosome

4.3 Structure of the chromosome

4.4 Composition of the chromosome

4.5 Types of chromosomes

4.6 Chromosomal aberrations-numerical and structural

5. Sex Determination

5.1 Sexual dimorphism in animals

5.2 Chromosomal theory of sex determination

5.3 Environmental sex determinations

6. Human Genetics

6.1 Karyotype

6.2 Syndromes

6.3 Inborn errors of metabolism

7. Sex Linked Inheritance in Human

7.1 Colour blindness

7.2 Haemophilia

7.3 Hypertrichosis

7.4 Sex influenced genes

8. Cytoplasmic Inheritance

8.1 Characteristics of cytoplasmic inheritance

9. Application of Genetics

9.1 Eugenics

9.2 Somatic cell hybridization

9.3 Cloning and transgenic animals

9.4 DNA fingerprinting and gene therapy